Addressing Stigma to End the HIV Epidemic in the U.S. | HRSA 25 060

Opportunity Information: Apply for HRSA 25 060

The Addressing Stigma to End the HIV Epidemic in the U.S. opportunity (HRSA-25-060) is a discretionary federal funding program run by the Health Resources and Services Administration (HRSA) as a cooperative agreement, with collaboration and aligned expertise from NIH and CDC. The core purpose is to expand access to stigma-free, high-quality HIV prevention, care, and treatment by tackling stigma and discrimination that keep people from entering care, staying in care, or achieving the best possible health outcomes. The program is specifically oriented toward people who have not been successfully maintained in HIV care and toward communities that experience higher rates of HIV in the United States, recognizing that stigma operates at multiple levels (social, structural, and organizational) and directly affects service uptake, quality of care, and patient trust.

HRSA plans to fund one recipient to act as the national Implementation, Capacity, and Evaluation Provider. This single awardee functions like a backbone organization for the initiative: it will deliver training, build capacity, and provide hands-on support to demonstration sites (which will participate as subrecipients). A key feature is the use of an implementation science approach, meaning the awardee and demonstration sites will not only select or design anti-stigma interventions, but will systematically adapt them for local settings, implement them with attention to real-world constraints, evaluate what works (and why), and then disseminate the resulting tools and lessons so other HIV service organizations can replicate or tailor them. In practice, this makes the project both a service improvement effort and a learning-and-spread effort, aiming to produce actionable approaches that can be adopted across diverse organizations and communities.

The stated objectives make clear that the initiative is meant to shift organizational culture and everyday practice, not just raise awareness. First, it seeks to strengthen and promote a culture of anti-stigma across HHS-funded organizations providing HIV-related services, which implies changes in norms, leadership expectations, policies, and routine operations. Second, it aims to increase the availability and dissemination of practical tools that HIV care, treatment, and prevention organizations can adopt and adapt to address stigma internally, including organizations connected to the Ryan White HIV/AIDS Program (RWHAP) and the Ending the HIV Epidemic in the U.S. (EHE) initiative. Third, it emphasizes increasing the use of evidence-informed anti-stigma interventions, pointing applicants toward approaches grounded in research and prior experience rather than one-off messaging campaigns. Fourth, it targets measurable reductions in stigmatizing practices and behaviors among providers and staff, tying stigma reduction directly to improved outcomes, such as better patient experiences, stronger engagement and retention in care, and higher-quality prevention and treatment services.

Eligibility is broad but limited to domestic organizations rather than individuals. Eligible applicants include public and private institutions of higher education; nonprofits with or without 501(c)(3) status; and government entities such as states, counties, cities or townships, special districts, and independent school districts. Public housing authorities and Indian housing authorities are eligible, as are Native American tribal governments (federally recognized) and Native American tribal organizations. For this funding notice, "domestic" includes the 50 states and the District of Columbia, Puerto Rico, the Northern Mariana Islands, American Samoa, Guam, the U.S. Virgin Islands, and the freely associated states listed in the notice (Federated States of Micronesia, Republic of the Marshall Islands, and Republic of Palau). Individuals are explicitly not eligible to apply.

Administratively, the opportunity is listed under Assistance Listing (CFDA) 93.928 and is structured as a cooperative agreement, which typically signals substantial federal involvement beyond a standard grant, such as active collaboration, ongoing guidance, and shared expectations around implementation and evaluation. The anticipated number of awards is one, reinforcing that the funded entity will serve as the central coordinating provider for training, implementation support, evaluation, and dissemination. The original application closing date is March 18, 2025, and the funding opportunity was created on January 16, 2025. The posted award ceiling is listed as 0 in the source data, which often indicates the ceiling is either not set in that field or is described elsewhere in the full notice of funding opportunity, so applicants usually need to confirm funding levels and budget parameters in the complete NOFO text.

Overall, the grant is designed to move stigma reduction from being an abstract goal to being an operational, testable, and scalable set of practices inside HIV service organizations. The single funded recipient is expected to help demonstration sites implement anti-stigma interventions with rigor, evaluate impact, and then spread effective tools and strategies broadly across HIV prevention and care systems, especially those connected to major federal HIV efforts like RWHAP and EHE.

• The Health Resources and Services Administration in the health sector is offering a public funding opportunity titled "Addressing Stigma to End the HIV Epidemic in the U.S." and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.928.
• This funding opportunity was created on 2025-01-16.
• Applicants must submit their applications by 2025-03-18. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• The number of recipients for this funding is limited to 1 candidate(s).
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Others.

Apply for HRSA 25 060

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