Opportunity Information: Apply for RFA NS 21 002

The NINDS Morris K. Udall Parkinson's Disease Research Center Without Walls (P20 Clinical Trial Optional) funding opportunity (RFA-NS-21-002) is an NIH exploratory grant mechanism designed to jump-start entirely new, multi-institutional research consortia focused on solving a major, clearly defined problem in Parkinson's disease (PD). Rather than funding mature center programs, this FOA is positioned as a planning and early initiation award: it supports the work needed to bring a high-caliber team together, formalize how the collaboration will operate across institutions, and generate enough early evidence and coordination to compete for a later, larger "Udall Center Without Walls" effort. The intent is to create a structured, goal-driven consortium that can remove a specific roadblock limiting progress in understanding PD or improving treatment.

Applications are expected to be tightly organized around an essential PD research challenge that is both fundamental and actionable. The strongest proposals will do four things well: identify a top-priority scientific or translational question in PD; assemble an exemplary, transdisciplinary consortium with the right mix of expertise to address that question; produce supportive preliminary data through feasibility-style efforts; and lay out a targeted strategy showing strong potential to break through a critical impediment to progress in PD. The research focus can include studies of related synucleinopathies only when those studies directly serve the central Parkinson's challenge, keeping PD as the anchor of the overall program.

A defining feature of this FOA is its emphasis on new collaborations. Funding is intended for newly formed consortia, not for continuing established teams or ongoing multi-investigator projects that are already functioning. In practical terms, the application needs to demonstrate that the consortium is being created or substantially newly configured for this opportunity, with a clear rationale for why the combined capabilities of the group are uniquely suited to solving the stated challenge. The consortium must be anchored by at least one investigator with recognized expertise in Parkinson's disease research, and it must also integrate at least one investigator whose primary expertise lies in a different, complementary field. This cross-pollination requirement is meant to bring in cutting-edge approaches, novel conceptual frameworks, or specialized methods that are not already typical within traditional PD research groups.

Leadership and team quality are central review considerations. The Program Director/Principal Investigator is expected to provide strong scientific vision as well as effective administrative oversight, reflecting the reality that "center without walls" models require disciplined coordination across sites. Participating investigators should be world-class experts in their respective domains, reinforcing that NINDS is looking for unusually strong teams capable of moving a difficult problem forward quickly once the consortium is established.

From an administrative standpoint, the opportunity is offered by the Department of Health and Human Services through NIH (specifically NINDS) under CFDA 93.853, categorized as a health-related discretionary grant. The award ceiling is listed as $300,000, with an expectation of around four awards. The FOA is broad in eligible applicant types, including a wide range of public and private higher education institutions, nonprofits (with or without 501(c)(3) status), for-profit organizations (including small businesses), and multiple levels of government entities, along with certain tribal governments and tribal organizations. The original posting reflects a creation date of July 15, 2020, and an original closing date of September 28, 2020.

Overall, this grant is best understood as a structured on-ramp to a larger NINDS Udall Center Without Walls program: it funds the early-stage consortium building, governance, and feasibility work needed to tackle a high-impact Parkinson's disease challenge with a deliberately cross-disciplinary, multi-institutional team.

  • The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "NINDS Morris K. Udall Parkinson's Disease Research Center Without Walls (P20 Clinical Trial Optional)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853.
  • This funding opportunity was created on Jul 15, 2020.
  • Applicants must submit their applications by Sep 28, 2020. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $300,000.00 in funding.
  • The number of recipients for this funding is limited to 4 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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