Supplement Opportunity to Support Population-Based Research Studies of Rare Cancers (Admin Supp) | PA 17 223

Opportunity Information: Apply for PA 17 223

The Supplement Opportunity to Support Population-Based Research Studies of Rare Cancers (Admin Supp) (Funding Opportunity Number PA 17 223) is a National Cancer Institute (NCI) administrative supplement program under the National Institutes of Health (NIH). It is designed to provide additional, targeted funding to existing, eligible NCI-supported grants so that current awardees can expand or accelerate their work in ways that specifically improve what is known about rare cancers. The central purpose is to strengthen population-based, hypothesis-driven research that can clarify either the causes of rare cancers (etiology) or what happens after diagnosis (post-diagnosis outcomes), such as survival, recurrence, treatment patterns, long-term effects, quality of life, and other measurable outcomes that can be studied across defined populations.

This opportunity is not a standalone, new investigator-initiated award; it is an administrative supplement, meaning the applicant must already hold an eligible NCI award and is requesting added funds to conduct additional aims that fit within the scope and goals of the parent grant while advancing rare cancer research. The emphasis on population-based and hypothesis-testing studies signals that NCI is looking for rigorous designs that leverage population-level data sources (for example, cancer registries, linked clinical and administrative datasets, large cohort studies, or other representative data systems) to answer specific scientific questions, rather than purely descriptive work. In practical terms, the supplement is meant to help teams add analyses, expand cohorts, improve ascertainment of rare cancer cases, incorporate follow-up needed to evaluate outcomes, or otherwise enhance the parent project to generate stronger evidence relevant to rare cancers.

The program sits within NIH’s broader health and education-related research funding portfolio and is listed under CFDA number 93.399. The funding instrument is a grant, and the opportunity category is discretionary. The posted award ceiling for the supplement is $150,000, indicating the maximum amount expected per award under this supplement mechanism. The original closing date listed for the opportunity was June 1, 2017, with a creation date of March 15, 2017, which places it as a time-bound announcement in that period (applicants typically should confirm any current reissues, extensions, or successor announcements if seeking to apply now).

Eligibility is broad across many U.S.-based organizational types that commonly participate in NIH funding, including state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations other than federally recognized governments; public housing authorities/Indian housing authorities; nonprofits with and without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; small businesses; and other eligible entities. The FOA also calls out additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, Indian/Native American tribal governments that are not federally recognized, and U.S. territories or possessions. This framing reflects an intent to encourage participation across a wide range of institutions, including those that serve underrepresented or specific community populations and organizations positioned to conduct population-based research.

At the same time, the announcement clearly restricts foreign involvement. Non-domestic (non-U.S.) entities (foreign organizations and foreign institutions) are not eligible to apply, non-domestic components of U.S. organizations are not eligible, and foreign components as defined by the NIH Grants Policy Statement are not allowed. In other words, the work supported under this supplement must be carried out without a foreign component and by eligible domestic applicants tied to an existing NCI award.

Overall, this supplement opportunity is best understood as NCI’s targeted push to quickly add capacity to ongoing research programs so they can address high-value questions in rare cancers using population-based methods. By funding additions to existing awards, NCI can leverage established teams, data infrastructure, and ongoing study operations to produce timely, hypothesis-driven evidence about why rare cancers occur and how patients fare after diagnosis, with the ultimate aim of improving knowledge that can inform prevention, clinical care, and survivorship efforts for cancers that are uncommon and therefore harder to study through traditional single-institution approaches.

• The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Supplement Opportunity to Support Population-Based Research Studies of Rare Cancers (Admin Supp)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.399.
• This funding opportunity was created on 2017-03-15.
• Applicants must submit their applications by 2017-06-01. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $150,000.00 in funding.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

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