Opportunity Information: Apply for PA 18 819
The Lab to Marketplace: Tools for Brain and Behavioral Research (R43/R44 - Clinical Trial Optional) opportunity (Funding Opportunity Number PA-18-819) is a National Institutes of Health (NIH) Small Business Innovation Research (SBIR) grant program designed to move promising brain and behavioral research technologies out of academic or other non-small business settings and into the hands of broader users through commercial dissemination. The main idea is to take tools that may already work in a research lab, then push them through the practical steps that make them ready for real-world adoption: improving reliability, hardening them for routine use, polishing usability, and preparing for distribution and support in a marketplace context.
The FOA specifically targets Small Business Concerns (SBCs) as the eligible applicants, meaning the applicant organization must qualify as a small business under SBIR rules. While the original invention or early-stage development may have come from a university or another non-small business research organization, the funding is oriented toward enabling a small business to take on the next stage of development that bridges the gap between a research prototype and a product-quality tool. The NIH is signaling that it is not just interested in new scientific findings, but in the practical engineering, validation, and user-centered refinement work that helps a tool become robust, user-friendly, and broadly usable by researchers or other end users.
A central expectation in this program is active partnership between the small business and the original technology developers. In practice, that usually means close collaboration with the academic lab or institutional team that created the tool, so that the small business can preserve the scientific intent while improving the tool for broader use. The FOA notes that this partnership can be structured in different ways, including arrangements such as multiple Program Directors/Principal Investigators (PDs/PIs), which is often used when both the original developer and the small business lead need to be meaningfully involved in the project leadership and decision-making. The emphasis on collaboration reflects the reality that successful technology transfer typically requires both deep domain knowledge (often held by the original developers) and product development and commercialization capability (typically stronger in a small business setting).
The activity falls under the NIH health research category (CFDA 93.242) and uses the grant funding instrument. The announcement is labeled as clinical trial optional, meaning applicants may propose projects that include a clinical trial if it is appropriate for the technology and development plan, but a clinical trial is not required. This is relevant for tools that might be validated in human subjects or clinical environments, but it also accommodates purely research-oriented tools that can be advanced without clinical trial structures.
In terms of eligibility and geographic restrictions, the program is aimed at U.S. small businesses. Non-domestic (non-U.S.) entities, including foreign institutions, are not eligible to apply, and non-domestic components of U.S. organizations are also not eligible to apply. At the same time, the FOA indicates that foreign components may be allowed as defined under the NIH Grants Policy Statement, which generally means a U.S. applicant might be permitted to include certain foreign collaborations or elements if they are justified and meet NIH policy requirements, but the applicant organization itself must be eligible as a U.S. small business.
From the administrative details provided, the opportunity was created on 2018-06-06 and had an original closing date of 2021-04-05. The award ceiling listed is $450,000, which suggests an upper bound on the amount anticipated per award under the provided summary data. The NIH expectation is that funded projects will focus on the development work needed to move a technology toward commercialization, which often includes improving performance and reliability, strengthening software or hardware design for broader deployment, enhancing documentation and user workflows, and positioning the tool for distribution, support, and uptake by the intended research community.
Overall, this FOA is best understood as a targeted bridge between lab innovation and market-ready research tools in the brain and behavioral sciences, with SBIR funding used to support small businesses that can professionalize and disseminate these technologies, ideally while working closely with the academic or original non-small business inventors who created them.Apply for PA 18 819
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Lab to Marketplace: Tools for Brain and Behavioral Research (R43/R44 - Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242.
- This funding opportunity was created on 2018-06-06.
- Applicants must submit their applications by 2021-04-05. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $450,000.00 in funding.
- Eligible applicants include: Small businesses.
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| Modeling and Simulation to Optimize HIV Prevention Research (MS OPR) (R01 Clinical Trial not allowed) Apply for RFA AI 18 026 Funding Number: RFA AI 18 026 Agency: National Institutes of Health Category: Health Funding Amount: $400,000 |
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